Super Vidalista is marketed as a combination product containing tadalafil and dapoxetine. Because tadalafil can lower blood pressure, combining it with alpha-blockers may increase the risk of dizziness, fainting, or symptomatic hypotension. Official tadalafil information recommends caution when tadalafil is used for erectile dysfunction in people taking alpha-blockers.

Patients should generally be stable on their alpha-blocker treatment before tadalafil is introduced, and tadalafil should be started at the lowest recommended dose.

People who should not combine these medicines without medical supervision include those who already have low blood pressure, experience frequent dizziness or fainting, or take an alpha-blocker together with other blood-pressure-lowering medicines. Extra caution is also appropriate for people with significant cardiovascular conditions.

Alpha-blockers such as tamsulosin, alfuzosin, doxazosin, and terazosin are prescribed for conditions including urinary symptoms associated with an enlarged prostate and, in some cases, high blood pressure. The interaction is particularly important because both medicines can relax blood vessels and lower blood pressure.

Tadalafil is not recommended with alpha-blockers for treating benign prostatic hyperplasia (BPH) because of the potential for blood-pressure lowering and insufficient evidence supporting the combination for that indication.

Anyone taking an alpha-blocker should tell their doctor or pharmacist before using Super Vidalista. Do not stop an alpha-blocker suddenly or change either medicine's dose without professional advice.

Seek urgent medical attention for severe dizziness, fainting, chest pain, or an erection lasting longer than four hours.

Overall, Super Vidalista should be combined with an alpha-blocker only when a healthcare professional has determined that the combination and dosing are appropriate.