Duratia 90 mg, which contains Dapoxetine, is used primarily for the treatment of premature ejaculation. Like many medications, it can interact with other drugs, which may affect how it works or increase the risk of side effects. Here are some common types of interactions:

Antidepressants: Combining Duratia with other antidepressants (such as SSRIs or SNRIs) can increase the risk of serotonin syndrome, a potentially serious condition caused by excessive levels of serotonin in the brain.

CYP3A4 Inhibitors: Duratia 90mg is metabolized by the CYP3A4 enzyme. Drugs that inhibit this enzyme (like certain antifungals, antibiotics, or HIV medications) can increase the levels of Duratia in the blood, raising the risk of side effects.

Monoamine Oxidase Inhibitors (MAOIs): Using Duratia with MAOIs can increase the risk of serotonin syndrome.

Other Medications for Sexual Dysfunction: Combining Duratia with other medications used to treat erectile dysfunction (such as PDE5 inhibitors like Viagra) should be done with caution, as it can increase the risk of side effects.

Alcohol: While not a drug interaction per se, consuming alcohol can affect the effectiveness of Duratia and increase the risk of side effects such as dizziness or drowsiness.

It’s crucial to consult with a healthcare provider before starting, stopping, or combining Duratia with other medications. They can provide personalized advice based on your specific health needs and any other medications you may be taking.