What Are the Differences Between Sildenafil and Bioglandin Injection ?


Sildenafil and Bioglandin Injection are both treatments for erectile dysfunction (ED), but they differ significantly in their composition, method of administration, mechanism of action, duration of effect, and suitability for different patients. Here’s a comprehensive comparison of these two treatments:

1. Composition and Mechanism of Action
Sildenafil:

Composition: Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. It is the active ingredient in medications such as Viagra and is also found in other ED treatments like Sildenafil tablets.
Mechanism of Action:
Sildenafil works by inhibiting the PDE5 enzyme, which leads to increased levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum. This causes relaxation of the smooth muscles and dilation of blood vessels in the penis, enhancing blood flow and helping achieve and maintain an erection in response to sexual stimulation.
Bioglandin Injection:

Composition: The active ingredient in Bioglandin Injection is Alprostadil, a synthetic form of prostaglandin E1 (PGE1).
Mechanism of Action:
Alprostadil directly relaxes the smooth muscle tissue in the blood vessels of the penis, increasing blood flow and causing an erection. Unlike oral medications, it does not rely on sexual stimulation to be effective.